Unlike enzyme based cleaners, this product is formulated to target human and pet urine. It will remove pheromones, the sticky mucous left in dog marking and get out the toughest stains and odors. Once you apply the product, Do-Not reapply before two weeks. Adding more product before two weeks will stop the product from digesting the problems you are attempting to remove. If after two weeks the problem still exist than you need to get the liquid to the source of the problem. A Pet Urine Locator blacklight works great to find urine marking. Shine the blacklight about thirty inches above the ground at night and look for glowing areas. Treat with Poop-Off Superior Stain and Odor Remover.